Description
This Chicken Alfredo Lasagna is the ultimate comfort food with a creamy twist! Layers of tender chicken, rich spinach Alfredo sauce, and gooey mozzarella cheese create a decadent lasagna that’s perfect for family dinners or special occasions. It’s flavorful, satisfying, and completely ricotta-free — perfect for anyone craving a creamy, cheesy, and hearty meal.
Ingredients
12 lasagna noodles (oven-ready or cooked al dente)
2 lbs boneless chicken breasts or thighs
2 tbsp olive oil
1 tsp salt
1 tsp black pepper
1 tsp garlic powder
1 tsp Italian seasoning
4 tbsp butter
4 cloves garlic, minced
3 tbsp all-purpose flour
2 cups whole milk
1 cup heavy cream
4 cups fresh spinach, roughly chopped
1 ½ cups freshly grated Parmesan cheese
3 cups shredded mozzarella cheese
½ tsp red chili flakes (optional)
Additional salt and pepper to taste
Instructions
Season and Cook the Chicken:
Coat chicken with olive oil, salt, pepper, garlic powder, and Italian seasoning.
Sauté in a skillet over medium heat for 5-7 minutes per side until golden and cooked through. Rest, then chop or shred.
Prepare the Spinach Alfredo Sauce:
Melt butter in a large saucepan. Sauté minced garlic until fragrant.
Stir in flour and cook for 1 minute. Gradually whisk in milk and cream until smooth.
Add spinach and simmer until wilted. Stir in Parmesan cheese, season with salt, pepper, and optional chili flakes.
Assemble the Lasagna:
Preheat oven to 375°F (190°C).
Spread a thin layer of Alfredo sauce on the bottom of a greased 9×13 baking dish.
Layer lasagna noodles, Alfredo sauce, cooked chicken, and mozzarella cheese. Repeat layers, finishing with sauce and mozzarella on top.
Bake:
Cover with foil and bake for 35-40 minutes.
Uncover and bake an additional 7-10 minutes until the top is golden and bubbly. Optional: Broil for 2-3 minutes for extra color.
Rest and Serve:
Let the lasagna rest for 10-15 minutes before slicing for perfect layers. Enjoy!
Notes
- Add mushrooms, broccoli, or zucchini between layers for extra veggies.
- Swap chicken with shrimp or crab for a seafood version.
- Use zucchini slices instead of noodles for a low-carb, keto-friendly twist.
- This lasagna freezes well — perfect for make-ahead dinners or meal prep.
- Reheat leftovers covered at 350°F to preserve the creamy texture.
- Prep Time: 30 minutes
- Cook Time: 50 minutes
- Cuisine: Italian-American
Nutrition
- Calories: 680 kcal per serving
- Fat: 38g
- Carbohydrates: 32g
- Protein: 50g